Go directly to:

1. Dosing guidance
2. Therapy initiation
3. Additional resources

Working with your clinical team to adopt protocols and set expectations can help support initiation of VENCLEXTA. Use this guide to help prepare your practice and patients for treatment. 

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1. Dosing guidance

Dosing schedule, drug interactions, dose modifications

Follow the links below to find information to help you understand and plan dosing for your patients and watch an oncologist talk about dosing for a patient with R/R CLL.

VENCLEXTA Starting Pack
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Dosing schedules

See the 5-week ramp-up and fixed-duration regimens for 1L and R/R 1

View schedules ›
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Drug interactions

Review drug interactions, associated dose modifications, and contraindications

Get information ›
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Dosing modifications

Learn how to manage potential adverse reactions

Review dose modifications ›
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After the dose ramp-up, Mark* will take 24 months of VENCLEXTA daily at 400 mg/day and 6 cycles of rituximab with 375 mg/m2 in Cycle 1 and 500 mg/m2 in Cycles 2-6.
-Dr. Edward Crane, TriHealth Cancer Institute, Cincinnati, OH

*Hypothetical patient.


Hear Dr. Crane discuss dosing for a relapsed/refractory patient case.

Watch video
Video thumbnail - Hear Dr. Crane discuss Dosing for a relapsed/refractory patient case.
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2. Therapy initiation

Risk assessment, prophylaxis, and monitoring measures for TLS

When you’re ready to start VENCLEXTA, here is information to help you assess, prep, and initiate your patients.

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Tumor Burden Assessment tutorial

Use this interactive tutorial to understand how to assess tumor burden as well as the ramp-up and monitoring protocol to follow.

Try it now
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My biggest piece of advice…is to educate your team, educate your patients, and simply be prepared.
-Christina Patterson, PA-C, Cancer Care Associates of York, York, PA


Hear Christina Patterson, PA-C, discuss the steps for VENCLEXTA initiation.

Watch video
Video thumbnail - Christina Patterson VENCLEXTA initiation discussion
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3. Additional resources

Resources for you and your patients

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Financial, prior authorization, and ordering information

Learn about the support available for you and your patients

View programs ›
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Treatment guide

Get your copy of this comprehensive guide to VENCLEXTA treatment

Download ⬇
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Patient calendar

Customizable VENCLEXTA calendar to help support patient adherence to therapy

Download ⬇
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Educational resource for patients with CLL

Downloadable brochure for patients with previously untreated or R/R CLL

Download ⬇
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Patient support

Learn about support for your patients throughout therapy

View support ›
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Contact a representative

Get answers to your VENCLEXTA questions

Find a rep ›

R/R=relapsed/refractory; CLL=chronic lymphocytic leukemia; 1L=first-line; TLS=tumor lysis syndrome.