*Censoring for missing PFS assessments, intent to treat (ITT).
HR estimate is based on Cox proportional hazards model stratified by 17p deletion, risk status, and geographic region; p-value is based on log-rank test stratified by the same factors.
HR=hazard ratio; CI=confidence interval

  • After a median follow-up of 23.4 months (range: 0-37.4+), there were 35 events in the VEN+R arm (26 progression and 9 death events) compared with 106 events in the BR arm (91 progression and 15 death events) 2
  • The median PFS was not reached with VEN+R vs 18.1 months (95% CI: 15.8-22.3) with BR 2
  • The estimated 24-month PFS was 83% (95% CI: 77-89) for VEN+R vs 39% (95% CI: 31-48) for BR 8*

Overall survival: At the time of analysis, the median overall survival had not been reached in either arm after a median follow-up of 22.9 months. 2